Table 2 Correlation between miR-143-3p expression and clinicopathological features
Patient characteristics | MiR-143-3p expression | X2 | P value | ||
|---|---|---|---|---|---|
Low (n = 54) | High (n = 26) | ||||
Age | 0.887 | 0.346 | |||
Median | 60 | ||||
Range | 38–74 | ||||
< 60 | 34 | 21(38.9 %) | 13(50 %) | ||
≥ 60 | 46 | 33(61.1 %) | 13(50 %) | ||
Gender | 3.242 | 0.072 | |||
Female | 18 | 9(16.7 %) | 9(34.6 %) | ||
Male | 62 | 45(83.3 %) | 17(65.4 %) | ||
Tumor location | 0.608 | 0.738 | |||
Upper | 12 | 7(13 %) | 5(19.2 %) | ||
Middle | 34 | 23(42.6 %) | 11(42.3 %) | ||
Lower | 34 | 24(44.4 %) | 10(38.5 %) | ||
Histological grade | 0.547 | 0.761 | |||
Poor | 33 | 22(40.7 %) | 11(42.3 %) | ||
Moderate | 31 | 20(37.0 %) | 11(42.3 %) | ||
Well | 16 | 12(22.2 %) | 4(15.4 %) | ||
pT status | 1.6222 | 0.444 | |||
pT1 | 12 | 10(18.5 %) | 2(7.7 %) | ||
pT2 | 25 | 16(29.6 %) | 9(34.6 %) | ||
pT3 | 43 | 28(20.2 %) | 15(57.5 %) | ||
Lymph node metastasis | 4.297 | 0.038* | |||
Absent (0) | 33 | 18(33.3 %) | 15(57.5 %) | ||
Present (1/2/3) | 47 | 36(66.7 %) | 11(42.3 %) | ||
TNM stage | 4.941 | 0.026* | |||
I/II | 38 | 21(38.9 %) | 17(65.4 %) | ||
III | 42 | 33(61.1 %) | 9(34.6 %) | ||