Table 3 Univariate analysis and multivariate analysis for prognostic factors in ESCC patients

Age (<60/≥60)

0.346

-

-

-

Gender (Female/Male)

0.22

-

-

0.785

Tumor location (Upper/Middle/Lower)

0.315

-

-

-

Clinical stage (I + II/III)

<0.001*

2.378

1.061–5.330

0.035*

Histological grade (Well/moderate/Poor)

0.045*

0.521

0.344–0.788

0.02*

Lymph node metastasis (Present/Absent)

<0.001*

1.96

0.845–4.547

0.117

MiR-143-3p expression (Low/High)

<0.001*

0.367

0.171–0.786

0.01*