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Table 3 Univariate analysis and multivariate analysis for prognostic factors in ESCC patients

From: MiR-143-3p functions as a tumor suppressor by regulating cell proliferation, invasion and epithelial–mesenchymal transition by targeting QKI-5 in esophageal squamous cell carcinoma

Variables Univariate analysis Multivariate analysis
  P value HR 95 % CI P value
Age (<60/≥60) 0.346 - - -
Gender (Female/Male) 0.22 - - 0.785
Tumor location (Upper/Middle/Lower) 0.315 - - -
Clinical stage (I + II/III) <0.001* 2.378 1.061–5.330 0.035*
Histological grade (Well/moderate/Poor) 0.045* 0.521 0.344–0.788 0.02*
Lymph node metastasis (Present/Absent) <0.001* 1.96 0.845–4.547 0.117
MiR-143-3p expression (Low/High) <0.001* 0.367 0.171–0.786 0.01*
  1. HR hazard ratio; 95 % CI 95 % confidence interval, *p < 0.05