Fig. 6
From: MiR-204 silencing in intraepithelial to invasive cutaneous squamous cell carcinoma progression
Immunolocalization of pY705-STAT3 in AK and cSCC. a pY705-STAT3 signal detected by immunofluorescence in CSE skin, two representative non-peritumoral AK lesions and in two AK lesions adjacent to cSCC. Scale bar, 50 μm. b Hematoxylin/eosin and pY705-STAT3 staining of cSCC. Observe the intense pY705-STAT3 signal in tumor areas closer to the skin surface whereas the signal is lost in more infiltrative deep regions of the tumor. Scale bar, 200 μm. c PTPN11 immunodetection in CSE skin, non-peritumoral AK and AK adjacent to cSCC. Scale bar, 50 μm