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Fig. 9 | Molecular Cancer

Fig. 9

From: RETRACTED ARTICLE: HOXA7 plays a critical role in metastasis of liver cancer associated with activation of Snail

Fig. 9

Snail is essential for HOXA-induced metastasis. a Western blot analysis of Snail in indicated cell lines. b qRT-PCR analysis of Snail in indicated cell lines. c Transwell and matrigel assay of HepG2-HOXA7 cell with silent expression of Snail. d Transwell and matrigel assay of HL-7702-HOXA7 cell with silent expression of Snail. e The total numbers of mice with distant metastasis at 60 days after injection of HepG2-HOXA7 cells with silent expression of Snail into tail vein. f HE stain for metastatic foci in lung with injection of HepG2-HOXA7 cell with silent expression of Snail. g Numbers of metastatic foci in lung with injection of HepG2-HOXA7 cell with silent expression of Snail. h Conclusion of regulatory mechanism of HOXA7 in this study. P < 0.01 based on the Student t test. Error bars, SD. The each number of replicates is 3

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