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Fig. 8 | Molecular Cancer

Fig. 8

From: Less is more: low expression of MT1-MMP is optimal to promote migration and tumourigenesis of breast cancer cells

Fig. 8

Overexpression of MT1-MMP in MDA-MB 231 cells negatively affected migration and viability (a) Immunoblot analysis (AB6004) showing pro-, active, and degradation forms of MT1-MMP in MDA-MB 231 breast cancer cells and three MDA-MB 231 cell lines expressing different levels of MT1-MMP. β-actin was used as a loading control. b Transwell migration assay of MDA-MB 231 MT1-MMP cells incubated in SF media for 12 h. c Viability of MDA-MB 231 MT1-MMP cell lines during incubation in media containing 10 % FBS (top) or serum free media (bottom) measured daily for 7 days using Celltiter96®

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Molecular Cancer

ISSN: 1476-4598