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Fig. 5 | Molecular Cancer

Fig. 5

From: Prediction of chemo-response in serous ovarian cancer

Fig. 5

Genomic position of 34 genes selected for the optimized prediction model. a The 34 most informative genes from the prediction model and their chromosomal location: chr: number of the chromosome were the gene is located; start: of the gene position; length: of the gene in base-pairs (bp). The human genome version was hg19. b Circular layout with matrix depiction of different biological variables. From external to internal: Chromosome bands: circular representation of all chromosomes (centromere is in red); d Differential gene expression between incomplete and complete responders (CR/IR; red is over-expressed, green is under-expressed); c Differential DNA methylation between CR and IR (CR/IR; blue is hypomethylated, orange is hyper methylated); b Differential miRNA expression between CR and IR (CR/IR; red is over-expressed, grey is under-expressed); a Gene copy number variation between CR and IR (copy gain is red, green is copy loss). The order of genes in a is the same as in b. Lines represent correlations between different biological variables (for more details see Table 4)

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