Table 5 Pathway enrichment analysis of the selected 34 genes constituting the simplified prediction model
Cluster Profiler pathway enrichment analysis | ||||
KEGG ID | Description | Adjusted p-value | FDR q-value | Gene IDs |
hsa03030 | DNA replication | 2.07E-02 | 7.28E-03 | POLE/MCM5 |
hsa04974 | Protein digestion and absorption | 3.09E-02 | 1.08E-02 | PRSS1/PRSS2 |
hsa03010 | Ribosome | 3.09E-02 | 1.08E-02 | RPS23/RPS20 |
hsa00240 | Pyrimidine metabolism | 3.09E-02 | 1.08E-02 | POLE/ENTPD5 |
hsa04972 | Pancreatic secretion | 3.09E-02 | 1.08E-02 | PRSS1/PRSS2 |
GeneGO pathway enrichment analysis | ||||
# | Description | Adjusted p-value | FDR q-value | Gene IDs |
1 | Cell adhesion_Chemokines and adhesion | 8.45E-03 | 9.91E-02 | Thrombospondin 1, TRIO |
2 | Immune response_IL-12 signaling pathway | 3.21E-02 | 9.91E-02 | G6NT |
3 | Cytoskeleton remodeling_Role of PDGFs in cell migration | 3.34E-02 | 9.91E-02 | PDGF-D |
4 | Triacylglycerol metabolism p.2 | 3.89E-02 | 9.91E-02 | CEL |
5 | Development_Thrombospondin-1 signaling | 3.89E-02 | 9.91E-02 | Thrombospondin 1 |
6 | Cell cycle_Start of DNA replication in early S phase | 4.43E-02 | 9.91E-02 | MCM5 |
7 | Role of Tissue factor in cancer independent of coagulation protease signaling | 4.84E-02 | 9.91E-02 | Thrombospondin 1 |