Fig. 2
From: Systems analysis identifies miR-29b regulation of invasiveness in melanoma
Many putative miR-mRNA relationships involve mRNAs previously implicated in EMP and melanoma phenotype switching. LM-MEL and TCGA (top and bottom subplots, respectively) transcript abundance data for (a-h) selected, previously validated relationships (miRTarBase, ‘strong experimental evidence’; see Methods/Databases), and (i-q) putative relationships regulating mRNAs implicated in melanoma phenotype switching by Widmer et al. [3]. Further details are given in Additional file 4. Predicted regulatory interactions involving SOX transcription factors integral to melanoma phenotype switching are shown (r-s).