Fig. 2From: Cancer stem cell metabolism: a potential target for cancer therapyImpact of glucose utilisation by CSCs and non CSCs highlights the difference in their metabolic profiles. Pyruvate enters the TCA cycle to initiate the precursor or supply towards biosynthetic reactions. The Warburg effect in turn activates aerobic glycolysis and lessens mitochondrial respiration, suggesting a preferred choice for proliferation.Back to article page