Fig. 4
From: miR-375 induces docetaxel resistance in prostate cancer by targeting SEC23A and YAP1
Expression of miR-375 and its target genes (YAP1 and SEC23A) in PC cells or xenograft tumors. a qRT-PCR analysis showed that YAP1 and SEC23A expressions were downregulated after miR-375 transfection in PC-3 cells. * indicates statistically significant reduction. b Western blots showed suppression of YAP1 and SEC23A proteins in the miR-375-transfected PC-3 cells. c qRT-PCR analysis showed that YAP1 and SEC23A expression levels were lower in xenografts overexpressing miR-375. d Western blots showed suppression of YAP1 and SEC23A proteins in xenograft tumors overexpressing miR-375. β-actin served as a loading control to normalize protein signal intensity