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Table 1 Secreted levels of 5-HT and VEGF from MDA-MB-231 cells in culture and their inhibition by BJ-1113

From: Tryptophan hydroxylase 1 and 5-HT7 receptor preferentially expressed in triple-negative breast cancer promote cancer progression through autocrine serotonin signaling

 

VEGF (ng/mg protein)

5-HT (ng/mg protein)

Vehicle

1.9 ± 0.2

28.6 ± 0.4

BJ-1113 (μM)

0.1

1.3 ± 0.1

18.0 ± 0.8

1

1.1 ± 0.2

13.9 ± 0.4

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Molecular Cancer

ISSN: 1476-4598