Fig. 2
From: Cancer somatic mutations cluster in a subset of regulatory sites predicted from the ENCODE data
The chosen CRRs for NAB2 (ENST00000342556.5), STAT6 (ENST00000300134.2) and LRP1 (ENST00000243077.2). Black arrows link CRRs to the transcripts for which they were chosen in expression models; note that one CRR was chosen for both STAT6 and NAB2. Details of the chosen CRRs are given red boxes, including the bound transcription factors, sizes of the CRRs and mutations mapped from the COSMIC database. CRRs are labelled as enhancers if they show positive correlation with expression and repressors if they show negative correlation. The chosen CRRs are marked as red boxes if there is at least one reported mutation in them, and black otherwise