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Fig. 3 | Molecular Cancer

Fig. 3

From: Lipocalin2 suppresses metastasis of colorectal cancer by attenuating NF-κB-dependent activation of snail and epithelial mesenchymal transition

Fig. 3

LCN2 inhibits EMT characteristics in vitro and in vivo. a Western blots and real-time PCR analysis of EMT markers on LCN2 overexpression in SW620 or knockdown in SW480 cells, and quantification of relative mRNA expression of EMT markers and key proteins of corresponding cells (mean ± SD from at least three independent experiments). b Immunofluorescent staining of E-cadherin and Vimentin in corresponding cells. c Western blots and real-time PCR analysis of EMT characteristics in mouse xenografts (mean ± SD from at least three independent experiments). * P < .05, ** P < .01, scale bars, 100 μm

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