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Fig. 5 | Molecular Cancer

Fig. 5

From: Long non-coding RNA TUG1 is involved in cell growth and chemoresistance of small cell lung cancer by regulating LIMK2b via EZH2

Fig. 5

TUG1 affected cell growth and chemoresistance of small cell lung cancer by regulating LIMK2b. a qRT-PCR and western blot analysis for LIMK2b in H446DDP-shTUG1 and H69AR-shTUG1 cells transfected with LIMK2b-GFP (NC, LIMK2b-GFP). b CCK-8 proliferation assay were used to determine the cell viability (knockdown TUG1 while overexpression LIMK2b). c Representative images of Colony formation assays for proliferative cells knockdown TUG1 while overexpression LIMK2b. d Survival of H446DDP and H69AR cells transfected with shTUG1 while overexpression LIMK2b significantly increased compared with those transfected with negative control or mock transfected after treatment of CDDP, ADM or VP-16

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Molecular Cancer

ISSN: 1476-4598