Long non-coding RNA TUG1 is involved in cell growth and chemoresistance of small cell lung cancer by regulating LIMK2b via EZH2

Table 1 Association of TUG1 expression and clinicopathological characteristics in 33 SCLC patients

Characteristics	Total (n = 33)	TUG1 expression		χ ²	P value*
Characteristics	Total (n = 33)	Low expression	High expression	χ ²	P value*
Gender				1.816	0.174
Male	26	15 (57.7)	11 (42.3)
Female	7	2 (50.0)	5 (50.0)
Age (years)				0.299	0.420
≤62 year	19	9 (47.4)	10 (52.6)
>62 year	14	8 (57.1)	6 (42.9)
Smoking history				3.529	0.032
YES	20	7 (35.0)	13 (65.0)
NO	13	10 (76.9)	3 (23.08)
Disease stage				6.651	0.011
Limited disease (LD)	16	12 (75.0)	4 (25.0)
Extensive-stage disease (ED)	17	5 (29.4)	12 (70.6)
Status				4.520	0.036
Survival	10	8 (80.0)	2 (20.0)
Death	23	9 (39.1)	14 (60.9)

*For analysis of correlation between of TUG1 expression levels and clinical features, Fisher’s Exact Test were used. Results were considered statistically significant at P <0 .05

ISSN: 1476-4598