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Fig. 1 | Molecular Cancer

Fig. 1

From: MicroRNA expression patterns and signalling pathways in the development and progression of childhood solid tumours

Fig. 1

Proposed schematic of early developmental processes linking key signalling pathways and miRNA expression. a The developmental signalling pathway expression in early stages of development (Carnegie stages 1–9), and the miRNAs demonstrated to regulate these pathways during these stages. b Carnegie stages 10–17, representing further development and miRNAs ubiquitously expressed in all tissues (except heart and vessels). The three germ layers are represented and their associated body systems and organs are discussed in a cancer context in this review (kidney; WT, bone; OS, Neural crest; NB, brain; embryonal brain tumours, liver; HB). Additionally miRNAs associated with each organ/body system are presented

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Molecular Cancer

ISSN: 1476-4598