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Fig. 3 | Molecular Cancer

Fig. 3

From: LincRNAFEZF1-AS1 represses p21 expression to promote gastric cancer proliferation through LSD1-Mediated H3K4me2 demethylation

Fig. 3

FEZF1-AS1 promoted gastric cancer cells proliferation in vitro and vivo. a MTT assays were used to determine the cell viability for si-FEZF1-AS1 and pCDNA-FEZF1-AS1 transfected AGS, SGC-7901 and MGC-803 cells. Values represented the mean ± SD; from three independent experiments. b Colony-forming assays were conducted to determine the proliferation of si-FEZF1-AS1 and pCDNA-FEZF1-AS1 transfected AGS, SGC-7901 and MGC-803 cells. Values represented the mean ± SD; from three independent experiments. c Effects of FEZF1-AS1 downexpression on tumor growth in a xenograft mouse model. Empty vector or sh- FEZF1-AS1 was transfected into SGC-7901 cells, which were injected in the nude mice (n = 7), and the tumors were obtained at day 16 and weighed. *P < 0.05 and **P < 0.01. d The tumor sections were under H&E staining and IHC staining using antibodies against ki-67

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Molecular Cancer

ISSN: 1476-4598