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Table 4 Validity estimates for miR’s promoter methylation as markers for PCa in Cohort #1

From: MiR-193b promoter methylation accurately detects prostate cancer in urine sediments and miR-34b/c or miR-129-2 promoter methylation define subsets of clinically aggressive tumors

microRNA Sensitivity % (n positive/n total) Specificity (%) PPV (%) NPV (%) Accuracy (%)
miR-34b/c 94.4 (170/180) 86.7 98.8 56.5 93.8
miR-129-2 90.6 (163/180) 86.7 98.8 43.3 90.3
miR-152 79.4 (143/180) 86.7 98.6 26.0 80.0
miR-193b 90.0 (162/180) 100.0 100.0 45.5 90.8
miR-663a 84.4 (152/180) 100.0 100.0 34.9 85.6
miR-1258 97.8 (176/180) 100.0 100.0 78.9 97.9
  1. PCa Prostate cancer; PPV positive predictive value; NPV negative predictive value