Skip to main content
Fig. 1 | Molecular Cancer

Fig. 1

From: HOXC8 regulates self-renewal, differentiation and transformation of breast cancer stem cells

Fig. 1

Differential expression of homeobox genes in CSC compared to normal MaSC. a Unsupervised hierarchical clustering of 83 homeobox genes based on expression in CSC isolated by CD44+/CD24low/- cell sorting of different cell lines representing breast cancer molecular subtypes (LUM, HER2-E, TN), immortalised mammary epithelial cells (IMM) and normal mammary cells. Homeobox gene expression was determined by qRT-PCR using using the Homeobox Genes RT2 Profiler PCR Array (Qiagen) with two independent biological replicates. b Venn diagram representing differentially expressed genes unique or in common among CSC of different breast cancer molecular subtypes compared to normal MaSC (CD44+/CD24-/low cells from HMEC). Subtype-specific and common differentially expressed genes are indicated in the highlighted boxes

Back to article page