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Fig. 8 | Molecular Cancer

Fig. 8

From: HOXC8 regulates self-renewal, differentiation and transformation of breast cancer stem cells

Fig. 8

HOXC8 downregulation prevents differentiation of MCF10A cells induced by retinoic acid. a Representative FACS profiles and percentage of CD44+/CD24low/-, CD44+/CD24+, CD44−/CD24+ cells after retinoic acid (ATRA) treatment for 4 days and HOXC8 knockdown induced by doxycyclin (n = 3). Statistical analysis was performed by One-way ANOVA followed by Bonferroni’s multiple comparisons test. *P < 0.05, **P < 0.01, ***P < 0.001. b Representative FACS profiles and percentage of CD44+/CD24low/-, CD44+/CD24+, CD44−/CD24+ cells after retinoic acid (ATRA) treatment for 7 days and HOXC8 knockdown induced by doxycyclin (n = 3). Statistical analysis was performed by One-way ANOVA followed by Bonferroni’s multiple comparisons test. *P < 0.05, **P < 0.01, ***P < 0.001

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