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Fig. 2 | Molecular Cancer

Fig. 2

From: Doxycycline attenuates breast cancer related inflammation by decreasing plasma lysophosphatidate concentrations and inhibiting NF-κB activation

Fig. 2

BALB/c mice treated with Doxycycline (Dox) at 50 mg/kg/day showed significantly decreased concentrations of IL-1β, IL-6, IL-9, CXCL1, CXCL2, CXCL9, CCL2, CCL11, G-CSF, LIF and VEGF in the tumor. Concentrations of IL-1α, IL-2, IL-3, IL-4, IL-5, IL-7, IL-10, IL-12 (p40), IL-12 (p70), IL-13, IL-15, IL-17, CXCL5, CXCL10, CCL3, CCL4, CCL5, GM-CSF, IFNγ, M-CSF and TNFα were not affected by Dox. n = 6 for each group. Results are means ± SEM, * p < 0.05, ** p < 0.01 relative to control. Results were analyzed by a Student’s t-test

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Molecular Cancer

ISSN: 1476-4598