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Fig. 6 | Molecular Cancer

Fig. 6

From: Doxycycline attenuates breast cancer related inflammation by decreasing plasma lysophosphatidate concentrations and inhibiting NF-κB activation

Fig. 6

Effects of Doxycycline on PBMCs and RAW264.7 cells. a. Dox at 5 μg/ml suppressed the migration of mouse PBMCs induced by 1 μM of LPA and 100 ng/ml of CCL2. * p < 0.05 relative to basal level, # p < 0.05 relative to control. b. The effect of Dox on time course of phosphor-IκBα and total IκBα by 50 ng/ml of LPS in RAW264.7 cells. c. Quantification of phosphor-IκBα. d. Quantification of total IκBα. * p < 0.05 relative to control. Results are means ± SEM from three independent experiments. Results were analyzed by ANOVA with an SNK posthoc test

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Molecular Cancer

ISSN: 1476-4598