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Fig. 2 | Molecular Cancer

Fig. 2

From: KCNMA1 cooperating with PTK2 is a novel tumor suppressor in gastric cancer and is associated with disease outcome

Fig. 2

The difference of KCNMA1 methylation and expression between the gastric carcinoma and paired corresponding non-cancerous tissues, and the prognosis value. a Analysis of promoter methylation of KCNMA1 in gastric tumor tissues and paired corresponding normal tissues. The presence of PCR products in lane M indicates the presence of methylated alleles, and in lane U indicates the presence of unmethylated alleles. N = non-tumor, T = tumor; b BGS analysis also confirmed high levels of promoter methylation in a paired carcinoma tissues and corresponding normal tissues; Level of KCNMA1 mRNA (c) and protein (d) in the carcinoma and adjacent tissue; e The influence of KCNMA1 methylation on GC patients prognosis. N, normal tissues, T, gastric carcinoma

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