Mitochondrial DNA sequencing demonstrates clonality of peritoneal implants of borderline ovarian tumors

Table 2 Mitochondrial DNA mutations

Sample	Mitochondrial DNA Mutations	Mitochondrial DNA mutations localization	Mutation type	Amino Acid substitution	Gene	Variability	DS
B1	m.4810G >A	BOT	Nonsense	W114X	MT-ND2	0.0	-
B1	m.15570T >C	BOT + PI	Missense	L275P	MT-CYB	0.0	0.892
B2	m.3428G >A	BOT	Missense	G41D	MT-ND1	0.0	0.909
B2	m.15219insA	BOT	Frameshift	-	MT-CYB	0.0	-
B3	m.11984T >C	BOT + PI	Missense	Y409H	MT-ND4	0.002	0.764
B4	m.3352G >A	BOT	Missense	A16T	MT-ND1	0.0	0.827
	m.15449T >C	BOT + PI	Missense	F235L	MT-CYB	0.00642	0.088
	m.16189T >C	BOT + PI	SNP	-	MT-D-loop	0.767	-
B5	m.310insC	BOT	Insertion	-	MT-D-loop	0.215	-
B5	m.310delCC	PI	Deletion	-	MT-D-loop	0.215	-

All mitochondrial DNA mutations reported in the table are tumor-specific and heteroplasmic
Abbreviations: BOT Borderline Ovarian Tumor, PI Peritoneal Implant, SNP Single Nucleotide Polymorphism, DS Disease Score

ISSN: 1476-4598