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Fig. 3 | Molecular Cancer

Fig. 3

From: A loss of host-derived MMP-7 promotes myeloma growth and osteolytic bone disease in vivo

Fig. 3

MMP7 activity is decreased in the serum of myeloma-bearing mice or patients with multiple myeloma. Analysis of MMP7 activity in the serum of myeloma-bearing mice (a) or control and myeloma patients (b) was detected using an MMP7 activity assay. c MMP7 concentration in serum of control and myeloma patients, as measured by ELISA. An increase in the serum concentration of TIMP-1 was detected by ELISA in myeloma-bearing mice (d) and patients with multiple myeloma (e). Data are presented as mean. Mice; control n = 5; MM n = 6. Patients; control, n = 16; MM, n = 16. ns = not significant. Statistical analysis by Mann Whitney U test

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