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Table 2 Results of the univariate and multivariate analyses of prognostic factors for OS

From: MicroRNA-29c functions as a tumor suppressor by targeting VEGFA in lung adenocarcinoma

  Univariate analysis Multivariate analysis
Characteristic MST (mos) 5-y OS (%) p-value HR 95% CI p-value
Age    0.394    
  < 60 y 31.3 29.8     
   ≥ 60 y 37.9 35.0     
Sex    0.850    
 Male 34.6 30.0     
 Female 36.7 35.1     
ECOG performance status    0.987    
 0 36.7 30.0     
 1 34.0 34.0     
Weight loss    0.593    
  ≤ 5% 37.9 32.5     
  > 5% 31.6 25.0     
Smoking status    0.364    
 Smokers 34.6 25.8     
 Nonsmokers 36.7 35.7     
Tumor stage    0.005    0.033
 1 43.8 50.0   0.456 0.167–1.248 0.126
 2 40.7 35.4   0.441 0.237–0.818 0.009
 3 15.9 6.7     
Number of N2 station    0.029 0.654 0.387–1.104 0.112
 Single 49.3 38.2     
 Multiple 26.9 25.0     
Postoperative chemotherapy    0.629    
 Yes 34.2 31.5     
 No 43.8 36.4     
Postoperative radiotherapy    0.318    
 Yes 31.3 22.2     
 No 40.7 34.7     
MiR-29c expression    <0.001 3.694 2.106–6.479 <0.001
 Low 25.1 6.8     
 High 68.9 58.1     
  1. Abbreviations: OS overall survival, MST median survival time, mos months, HR hazard ratio, CI confidence interval