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Fig. 3 | Molecular Cancer

Fig. 3

From: Syndecan-1 is a novel molecular marker for triple negative inflammatory breast cancer and modulates the cancer stem cell phenotype via the IL-6/STAT3, Notch and EGFR signaling pathways

Fig. 3

Syndecan-1 silencing impairs the ability of 3D spheroids and colony formation in IBC SUM-149 and non-IBC SKBR-3 cells. Equal numbers of control and Syndecan-1-silenced SUM-149 and SKBR-3 cells were either plated on cultrex-coated petri dishes to form spheroids in 3D (a) or plated on 2D to form colonies (b). The right panels of A and B represent the quantification of the size of spheroids or the number of colonies as indicated. Data represent mean ± SEM, n = 3. ** P < 0.01 as determined by Student’s t-test

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Molecular Cancer

ISSN: 1476-4598