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Fig. 5 | Molecular Cancer

Fig. 5

From: Syndecan-1 is a novel molecular marker for triple negative inflammatory breast cancer and modulates the cancer stem cell phenotype via the IL-6/STAT3, Notch and EGFR signaling pathways

Fig. 5

Profiling of cytokines/chemokines and growth factors secreted by control and Syndecan-1 siRNA transfected SUM-149 cells. Media conditioned by secretome of control and Syndecan-1-depleted cells for 24 h were subjected to cytokine profiling using RayBio cytokine array-3, which detects 42 different cytokines. a A representative picture of the human cytokine protein membrane array for the secretions of control and Syndecan-1 siRNA transfectants. b Densitometric quantification of the signal intensity of each cytokine secreted by the cells. Control values were set to 1. Red boxes represent the predominant secreted cytokines namely, IL-6 (E3,4), IL-8 (G3,4), GRO (H1,2) and GRO-α (I1,2)

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