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Table 2 Serum miRNA expression associated with 2-year overall survival in patients with primary glioblastoma

From: Serum microRNA profiling in patients with glioblastoma: a survival analysis

 

Set one (N = 40)

Set two (N = 66)

Combined (N = 106)

microRNAs

Adj. HR (95% CI)a

P value

Adj. HR (95% CI)a

P value

Adj. HR (95% CI)a

P value

miR-630

1.69 (1.10, 4.57)

0.035

1.54 (0.74, 3.48)

0.473

1.62 (0.89, 3.41)

0.258

miR-106a-5p

1.68 (1.04, 4.83)

0.043

1.61 (1.02, 3.94)

0.046

1.71 (1.07, 3.63)

0.038

miR-20a-5p

1.60 (0.95, 4.95)

0.090

1.72 (1.05, 3.69)

0.045

1.69 (1.06, 3.79)

0.040

miR-17-5p

1.57 (0.94, 5.01)

0.096

1.81 (1.05, 3.98)

0.046

1.70 (1.05, 4.01)

0.043

miR-182

0.66 (0.28, 0.98)

0.049

0.67 (0.26, 0.98)

0.048

0.60 (0.29, 0.92)

0.037

miR-15b-5p

0.62 (0.30, 0.98)

0.049

0.86 (0.42, 1.65)

0.458

0.76 (0.40, 1.52)

0.402

miR-145-5p

0.57 (0.23, 0.92)

0.036

0.54 (0.25, 0.90)

0.037

0.59 (0.29, 0.88)

0.028

  1. aAdjusted by age, sex, ethnicity, smoking status, KPS score, timing of blood drawn, IDH1 mutation status, and BMI
  2. Data in bold are significant miRNAs
  3. Abbreviations: HR hazard ratio, CI confidence interval