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Table 2 Serum miRNA expression associated with 2-year overall survival in patients with primary glioblastoma

From: Serum microRNA profiling in patients with glioblastoma: a survival analysis

  Set one (N = 40) Set two (N = 66) Combined (N = 106)
microRNAs Adj. HR (95% CI)a P value Adj. HR (95% CI)a P value Adj. HR (95% CI)a P value
miR-630 1.69 (1.10, 4.57) 0.035 1.54 (0.74, 3.48) 0.473 1.62 (0.89, 3.41) 0.258
miR-106a-5p 1.68 (1.04, 4.83) 0.043 1.61 (1.02, 3.94) 0.046 1.71 (1.07, 3.63) 0.038
miR-20a-5p 1.60 (0.95, 4.95) 0.090 1.72 (1.05, 3.69) 0.045 1.69 (1.06, 3.79) 0.040
miR-17-5p 1.57 (0.94, 5.01) 0.096 1.81 (1.05, 3.98) 0.046 1.70 (1.05, 4.01) 0.043
miR-182 0.66 (0.28, 0.98) 0.049 0.67 (0.26, 0.98) 0.048 0.60 (0.29, 0.92) 0.037
miR-15b-5p 0.62 (0.30, 0.98) 0.049 0.86 (0.42, 1.65) 0.458 0.76 (0.40, 1.52) 0.402
miR-145-5p 0.57 (0.23, 0.92) 0.036 0.54 (0.25, 0.90) 0.037 0.59 (0.29, 0.88) 0.028
  1. aAdjusted by age, sex, ethnicity, smoking status, KPS score, timing of blood drawn, IDH1 mutation status, and BMI
  2. Data in bold are significant miRNAs
  3. Abbreviations: HR hazard ratio, CI confidence interval