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Table 3 Serum miRNA expression associated with 2-year disease free survival in patients with primary glioblastoma

From: Serum microRNA profiling in patients with glioblastoma: a survival analysis

  Set one (N = 40) Set two (N = 66) Combined (N = 106)
microRNAs Adj. HR (95% CI)a P value Adj. HR (95% CI)a P value Adj. HR (95% CI)a P value
miR-922 1.78 (1.09, 4.62) 0.040 1.39 (0.65, 3.72) 0.506 1.61 (0.75, 3.29) 0.369
miR-222-3p 1.77 (1.07, 4.85) 0.043 1.61 (1.02, 3.94) 0.046 1.71 (1.07, 3.63) 0.038
miR-20a-5p 1.66 (1.06, 4.45) 0.044 1.68 (1.02, 3.72) 0.045 1.68 (1.05, 3.81) 0.040
miR-106a-5p 1.61 (1.05, 4.39) 0.046 1.71 (1.09, 3.69) 0.039 1.72 (1.04, 3.76) 0.047
miR-124a 0.69 (0.27, 1.05) 0.084 0.63 (0.22, 0.97) 0.048 0.65 (0.26, 1.03) 0.062
miR-182 0.68 (0.28, 0.96) 0.047 0.67 (0.28, 0.97) 0.048 0.69 (0.30, 0.94) 0.043
miR-548a 0.68 (0.28, 0.99) 0.049 0.70 (0.29, 1.16) 0.242 0.61 (0.32, 1.04) 0.106
miR-371a-5p 0.64 (0.27, 1.26) 0.379 0.62 (0.29, 0.99) 0.049 0.62 (0.30, 1.05) 0.098
miR-145-5p 0.62 (0.28, 0.99) 0.049 0.56 (0.27, 0.97) 0.047 0.60 (0.32, 0.92) 0.039
  1. aAdjusted by age, sex, ethnicity, smoking status, KPS score, timing of blood drawn, IDH1 mutation status, and BMI
  2. Data in bold are significant miRNAs
  3. Abbreviations: HR hazard ratio, CI confidence interval