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Table 3 Serum miRNA expression associated with 2-year disease free survival in patients with primary glioblastoma

From: Serum microRNA profiling in patients with glioblastoma: a survival analysis

 

Set one (N = 40)

Set two (N = 66)

Combined (N = 106)

microRNAs

Adj. HR (95% CI)a

P value

Adj. HR (95% CI)a

P value

Adj. HR (95% CI)a

P value

miR-922

1.78 (1.09, 4.62)

0.040

1.39 (0.65, 3.72)

0.506

1.61 (0.75, 3.29)

0.369

miR-222-3p

1.77 (1.07, 4.85)

0.043

1.61 (1.02, 3.94)

0.046

1.71 (1.07, 3.63)

0.038

miR-20a-5p

1.66 (1.06, 4.45)

0.044

1.68 (1.02, 3.72)

0.045

1.68 (1.05, 3.81)

0.040

miR-106a-5p

1.61 (1.05, 4.39)

0.046

1.71 (1.09, 3.69)

0.039

1.72 (1.04, 3.76)

0.047

miR-124a

0.69 (0.27, 1.05)

0.084

0.63 (0.22, 0.97)

0.048

0.65 (0.26, 1.03)

0.062

miR-182

0.68 (0.28, 0.96)

0.047

0.67 (0.28, 0.97)

0.048

0.69 (0.30, 0.94)

0.043

miR-548a

0.68 (0.28, 0.99)

0.049

0.70 (0.29, 1.16)

0.242

0.61 (0.32, 1.04)

0.106

miR-371a-5p

0.64 (0.27, 1.26)

0.379

0.62 (0.29, 0.99)

0.049

0.62 (0.30, 1.05)

0.098

miR-145-5p

0.62 (0.28, 0.99)

0.049

0.56 (0.27, 0.97)

0.047

0.60 (0.32, 0.92)

0.039

  1. aAdjusted by age, sex, ethnicity, smoking status, KPS score, timing of blood drawn, IDH1 mutation status, and BMI
  2. Data in bold are significant miRNAs
  3. Abbreviations: HR hazard ratio, CI confidence interval