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Fig. 7 | Molecular Cancer

Fig. 7

From: Mesothelin promotes epithelial-to-mesenchymal transition and tumorigenicity of human lung cancer and mesothelioma cells

Fig. 7

MSLN regulates EMT and cancer stem cell traits. MSLN knockdown upregulates epithelial and adhesion molecules, and downregulates mesenchymal and CSC regulatory genes that mitigate self-renewal, proliferation, dissemination, and metastasis of cancer cells. Overexpression of MSLN in normal cells stimulates anchorage-independent growth, migration and invasion

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