Fig. 5From: TRIM8 restores p53 tumour suppressor function by blunting N-MYC activity in chemo-resistant tumoursSchematic representation of the opposite p53-TRIM8 and N-MYC-miR17-5p/miR106b-5p networks in cellular response to treatments. a, b Schematic representation of the molecular pathway that shows how TRIM8 recovery in TRIM8-deficient cells reactivates the p53 tumour suppressor pathway and blunts the N-MYC oncogenic activityBack to article page