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Table 2 Clinical pathological parameters and expression of PinX1 for prognosis of NSCLC patients by univariate survival analysis (Long-rank test)

From: The depletion of PinX1 involved in the tumorigenesis of non-small cell lung cancer promotes cell proliferation via p15/cyclin D1 pathway

Variable

Learning cohort

Validation cohort

Cases

Mean survival (months)

Media survival (months)

P-value*

Cases

Mean survival (months)

Media survival (months)

P-value*

Age(years)

ā€ƒ<56a

42

27.6

25

0.199

22

26.3

21

0.899

ā€ƒā‰„56a

51

31.8

29

29

25.6

22

Gender

ā€ƒMale

61

29.4

27

0.996

35

24.2

19

0.385

ā€ƒFemale

32

29.7

26

16

29.6

22

Smoking Condition

ā€ƒSmoker

42

22.5

18

0.000

20

20.1

17

0.042

ā€ƒNonsmoker

51

35.4

33

31

29.7

27

WHO grade

ā€ƒG1

28

28.1

21

0.942

16

17.5

14

0.012

ā€ƒG2

37

30.3

27

20

26.4

22

ā€ƒG3

28

29.8

32

15

34.2

29

Histological Type

ā€ƒSquamous cell carcinoma

37

26.5

21

0.293

22

21.3

18

0.252

ā€ƒAdenocarcinoma

46

29.8

27

23

28.2

24

ā€ƒOthers

10

36.5

32

6

35.2

27

T stage

ā€ƒT1-T2

38

39.1

37

0.000

18

31.6

31

0.009

ā€ƒT3-T4

55

22.4

16

33

23.3

19

N stage

ā€ƒN0

26

43.4

49

0.000

16

35.6

27

0.011

ā€ƒN1-N3

67

24.1

21

35

21.4

18

M stage

ā€ƒM0

66

35.6

34

0.000

35

30

25

0.004

ā€ƒM1

27

15

12

16

17

15

TNM stage

ā€ƒI-II

25

38.9

38

0.003

14

36.5

27

0.008

ā€ƒIII-IV

68

26

24

37

21.8

18

PinX1 expression

ā€ƒNegative

56

24.8

21

0.008

27

19.4

18

0.005

ā€ƒPositive

37

36.2

34

24

32.6

28

  1. *Long-rank test aMean age; T tumor, N node, M metastases