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Fig. 7 | Molecular Cancer

Fig. 7

From: DC - SIGNR by influencing the lncRNA HNRNPKP2 upregulates the expression of CXCR4 in gastric cancer liver metastasis

Fig. 7

STAT5A promotes HNRNPKP2 expression. a, The levels of 29 transcription factors in BGC823 cells after DC-SIGNR knockdown by real-time PCR (up). The levels of 29 transcription factors in SGC7901 cells after DC-SIGNR overexpression by real-time PCR (middle). Western blot confirmed the protein level of STAT5A in BGC823 cells after DC-SIGNR knockdown and in SGC7901 cells after DC-SIGNR overexpression (down). b-c Real-time PCR confirmed the STAT5A expression and western blot analysis of STAT5A protein level in BGC823 cells after DC-SIGNR knockdown with si-STAT5A and in SGC7901 cells after DC-SIGNR overexpression with pCMV3-STAT5A. D, HNRNPKP2 expression in BGC823 cells after DC-SIGNR with si-STAT5A and in SGC7901 cells after DC-SIGNR overexpression with pCMV3-STAT5A is analyzed by real-time PCR

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Molecular Cancer

ISSN: 1476-4598