Fig. 1
From: Hsp90β promoted endothelial cell-dependent tumor angiogenesis in hepatocellular carcinoma
Correlation between Hsp90β and MVD. a Representative images of IHC staining for Hsp90β in tissue microarrays of human HCC at different stages (left, stage I; right, stage IV) showed weak expression in primary cancer tissues (stage I) and strong expression in metastatic tissues (stage IV). Black arrows point to microvessels. b MVD measured by immunostaining for CD31 in HCC tissue microarrays. MVD was higher in the Hsp90β-positive group than in the Hsp90β-negative group. Black arrows point to microvessels. c MVD and Hsp90β-positive stainings were quantified and the correlation was analyzed with Spearman correlation method (correlation coefficient: R = 0.226, P = 0.027)