Skip to main content
Fig. 2 | Molecular Cancer

Fig. 2

From: IGF2BP3 functions as a potential oncogene and is a crucial target of miR-34a in gastric carcinogenesis

Fig. 2

Overexpression of IGF2BP3 predicts poor prognosis in GC. a Over-expressed IGF2BP3 was related to worse overall outcome and significantly associated with first progression survival in primary GC samples from Kaplan Meier plotter. b In TCGA cohort, high IGF2BP3 expression showed a non-significance trend to predict unfavorable overall and recurrence free survival. c Left panel, representative immunohistochemistry images of IGF2BP3 in normal gastric epithelium tissues, intestinal-, diffuse type GC samples (original magnification × 100, insertion × 400). IGF2BP3 expression was mainly localized in the cytoplasm. Right panel, Kaplan-Meier plots of disease specific survival according to IGF2BP3 expression status. IGF2BP3 accumulation in cytoplasm (moderate/strong staining) was associated with poor disease specific survival in patients with GC (P = 0.012)

Back to article page