Fig. 2
From: Phosphorylation by mTORC1 stablizes Skp2 and regulates its oncogenic function in gastric cancer
Skp2 interacts with mTOR. a Endogenous mTOR interacts with exogenous Skp2. 293 T cells were transfected with the indicated plasmids and harvested for immunoprecipitation experiments. b Endogenous Skp2 interacts with exogenous mTOR. 293 T cells were transfected with the indicated plasmids and harvested for coimmunoprecipitation experiments. (c, d) 293 T cells were contransfected with indicated plasmids and harvested for immunoprecipitation assay, indicating N-terminal of Skp2 (amino acids 1–200) were required for the interaction between mTORC1 and Skp2