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Fig. 1 | Molecular Cancer

Fig. 1

From: Epigenetic down regulation of G protein-coupled estrogen receptor (GPER) functions as a tumor suppressor in colorectal cancer

Fig. 1

GPER expression was down regulated in CRC tissues. a GPER expression was examined by quantitative RT-PCR in 32 paired human colon cancer tissues and adjacent normal mucosa tissues (Cohort 1); b Typical immunohistochemical staining for GPER expression in a tumor and its adjacent tissue from a CRC patient in the commercial tissue microarray (Cohort 2, left 10 X, right 40 X); c Scores for GPER staining in tumor and adjacent normal tissue samples from CRC patients in the commercial tissue microarray (Cohort 2); d Overall survival (OS) in patients with high/medium levels of GPER (n = 54) vs the remaining patients (n = 36) was plotted by the Kaplan-Meier method; e The relative mRNA expression of GPER in three Oncomine datasets: Skrzypczak Colorectal 1, Skrzypczak Colorectal 2, and Sabates-Bellver Colon

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