Fig. 6From: Epigenetic down regulation of G protein-coupled estrogen receptor (GPER) functions as a tumor suppressor in colorectal cancerActivation of GPER suppressed the in vivo progression of CRC. a The tumor volumes of G-1 and control group were measured in HCT-116 xenograft models at the indicated time interval; b The tumor volumes of G-1 and control group at the end of experiment; c The tumor tissue sections of G-1 and control group of HCT-116 xenograft models were subjected to IHC detection of Ki-67, p65, p-ERK1/2, and p27; d A proposed model to illustrate the mechanisms of GPER mediated growth suppression of CRC cellsBack to article page