Fig. 3
From: HN1 contributes to migration, invasion, and tumorigenesis of breast cancer by enhancing MYC activity
HN1 promotes the self-renewal of BCSCs and migration and invasion of breast cancer cells. a Mammosphere formation analysis for the self-renewal ability of BCSCs with HN1 overexpression (*P <0.05). b SP analysis for the self-renewal ability of BCSCs with HN1 overexpression. c Flow cytometry analysis of the relative size of the CD24−CD44+ population after HN1 overexpression. d Wound healing assay showing the migration ability of MCF-7 and T47D with HN1 overexpression. e Transwell invasion analysis showing the invasion ability of indicated cells with HN1 overexpression (*P < 0.05). f Correlation of HN1 mRNA levels and the gene signatures about breast cancer relapse in brain using GSEA (*P <0.05). Each bar represents mean ± SD of 3 independent experiments