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Table 1 Exosomes serve as biomarkers of OC

From: The emerging roles and therapeutic potential of exosomes in epithelial ovarian cancer

Exo-related Content Effect Research subjects Refer.
MiRNA miR-222-3p M2 polarization
EOC patients
healthy individuals
miR-21 oncogenesis
diagnostic tool
OSC cases and cystadenoma and normal ovaries [23]
miR-373 miR-200a miR-200b miR-200c diagnosis
EOC patients
healthy women
miR-92a diagnosis OC patient urine samples [25]
miR-30a-5p diagnosis
(high specificity)
OSA patient urine samples
GC and CC patients
Proteins 1017 proteins protein biomarkers OVCAR-3 and IGROV1 cells [29]
cluster of spliceosomal proteins prognostic markers OC ascites and cirrhotic ascites [30]
EpCAM diagnosis
women with malignant and benign ovarian disease
OC patients
CD24 early detection
ovarian carcinoma ascites
OC patients
ALCAM aggression biomarker EOC ascites [37]
IgG diagnosis women with OC and benign ovarian [38]
claudin-4 detection OC patients and healthy volunteers [39]
enzymes (G6PD, TK, TA1) diagnosis
OVCA429 and HO8910PM ovarian cell lines [40]
glycoproteins biomarker ovarian carcinoma OVM cells [41]