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Fig. 6 | Molecular Cancer

Fig. 6

From: PIK3CA hotspot mutations differentially impact responses to MET targeting in MET-driven and non-driven preclinical cancer models

Fig. 6

Impact of single and dual MET/PI3K blockade on colony-forming and wound-healing ability. a, colony forming assays in presence of EC50 concentrations for each drug (left: colony quantification; right: representative images). b, wound-healing assays. Cells were plated in complete medium and left to attach overnight in the presence of stoppers that create a central area of 2 mm. Stoppers were removed and cells were treated with vehicle (medium) or SF/HGF for 6 h. After this period, drugs were added to the medium and wound-healing was evaluated at 48 h

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