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Fig. 3 | Molecular Cancer

Fig. 3

From: MicroRNA-608 inhibits proliferation of bladder cancer via AKT/FOXO3a signaling pathway

Fig. 3

Overexpression of miR-608 inhibits the G1/S transition and cell cycle progression in Bca cells through AKT/FOXO3a signaling. a Flow cytometric analysis of cell cycle distribution. Overexpression of miR-608 resulted in a significant G1 phase arrest. b Western blot analysis. miR-608 down-regulated AKT/FOXO3a signaling related proteins in T24 and UM-UC-3 cell lines. c and d qRT-PCR analysis of the expression of CCND1 and CDK4 mRNA in BCa cells (T24 and UM-UC-3) after the transfection of miR-608. Error bars represent the S.D. from three independent experiments. *P < 0.05

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