Skip to main content

Table 1 The correlation of A2AR expression with clinicopathologic parameters in HNSCC

From: Blockade of adenosine A2A receptor enhances CD8+ T cells response and decreases regulatory T cells in head and neck squamous cell carcinoma

Parameters No. Mean ± SEM P value
Norma Mucosa 43 23.97 ± 4.106 Mucosa vs. Dys 0.9522
Dysplasia (Dys) 48 28.52 ± 4.661 Mucosa vs. PH < 0.001
Primary HNSCC (PH) 165 104.8 ± 6.823 Dys vs. PH < 0.001
Grade
 I 43 49.84 ± 9.083 I vs. II < 0.001
 II 84 115.8 ± 9.275 I vs. III < 0.001
 III 38 142.8 ± 15.00 II vs. III 0.2093
Lymph node involvement
 N0 105 85.53 ± 7.646 <0.001
 N1 + N2 60 138.6 ± 12.05  
Tumor Size
 T1 + T2 115 91.07 ± 7.109 0.002
 T3 + T4 50 136.5 ± 14.65  
Gender
 Male 129 104.7 ± 7.607 0.9610
 Female 36 105.5 ± 15.54  
Age
  < 50 44 98.84 ± 14.59 0.5976
  ≥ 50 121 107.0 ± 7.672  
HPV infection
 Negative 149 102.0 ± 7.011 0.2017
 Positive 16 131.5 ± 26.08  
 Primary HNSCC (PH) 165 104.8 ± 6.823 (reference)
 Recurrent HNSCC (Recurrence) 12 170.2 ± 28.35 0.0144
 HNSCC with inductive TPF chemotherapy (post TPF) 17 165.5 ± 18.40 0.0066
  1. Difference among three groups was analyzed by One-way ANOVO followed Tukey test. Difference between two groups was analyzed by un-paired or paired t test