Skip to main content

Table 4 Different combinations of the seven lists of HIF potential targets

From: In vitro downregulated hypoxia transcriptome is associated with poor prognosis in breast cancer

Combination

N

In this study

C1

p.v.

C2

p.v.

Comments

Union of all

1521

1172

42

0.26

145

1.2 × 10−38

-

Intersection of all

2

2

0

 

1

7.5 × 10−2

Gene RSBN1 in (C2)

Intersection of studies with HIF1α (L1, L2, L4, L5, and L6)

11

10

0

 

6

5.7 × 10−7

Genes in (C2): CA9, DARS, GAPDH, PLOD2, RSBN1, and SPRY1

In 3 lists or more

144

126

0

 

61

1.2 × 10−52

-

In 4 lists or more

60

49

0

 

30

1.5 × 10−30

-

In 5 lists or more

28

22

0

 

15

6.4 × 10−17

Genes in (C2): CA9, DARS, ENO1, GAPDH, GBE1, HK2, INHA, INSIG2, KIAA0195, P4HA1, PLOD2, RSBN1, SPRY1, STC2, WSB1

  1. The first column describes the combination of the lists, the second column shows the number of genes in the combination, the third column shows the number of those genes which are included in the input 15,588 genes in our study, the fourth and the fifth columns show the numbers of those genes which are included in C1 and C2, respectively, with their p-values, and the last column shows some comments