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Fig. 3 | Molecular Cancer

Fig. 3

From: MicroRNA-1296 inhibits metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by targeting SRPK1-mediated PI3K/AKT pathway

Fig. 3

miR-1296 inhibits the EMT process of HCC cells. a Western blot analysis of epithelial marker E-cadherin, and mesenchymal markers N-cadherin and Vimentin after miR-1296 overexpression in HCCLM3 cells. b IF staining of E-cadherin and Vimentin after miR-1296 overexpression in HCCLM3 cells. c miR-1296 knockdown decreased E-cadherin expression, and increased the levels of N-cadherin and Vimentin in Hep3B cells. d IF staining of E-cadherin and Vimentin after miR-1296 knockdown in Hep3B cells. e Immunohistochemistry of E-cadherin and Vimentin were showed and compared between miR-1296 high expressing HCC tissues and miR-1296 low expressing cases. *P < 0.05

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