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Fig. 5 | Molecular Cancer

Fig. 5

From: The noncoding RNA HOXD-AS1 is a critical regulator of the metastasis and apoptosis phenotype in human hepatocellular carcinoma

Fig. 5

ARHGAP11A expression contributes to the metastatic phenotype of HCC. a-d Transwell assays on miR19a-treated or ARHGAP11A-silenced HCCLM3 cells. e and f The expression levels of ARHGAP11A in cancerous and paired adjacent non-cancerous tissues in the non-metastatic and metastatic groups. g The expression levels of ARHGAP11A in non-metastatic and metastatic HCC tissues. h The correlation between HOXD-AS1 transcript levels and ARHGAP11A mRNA levels was measured in 44 HCC tissues. The dCt values (normalized to GAPDH) were subjected to Pearson correlation analysis. i and j The prognostic significance of ARHGAP11A in HCC patients. The Caner Genome Atlas project (TCGA) dataset was analyzed to reveal the effect of ARHGAP11A mRNA levels on the overall survival (OS) or disease-free survival (DFS) of patients with HCC using cBioPortal (http://cbioportal.org)

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Molecular Cancer

ISSN: 1476-4598