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Table 2 Multivariate analyses of factors associated with survival in 120 HCC patients

From: STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4

  

Multivariate

Variable

Univariate p

HR

95% CI

p-value

Sex: male vs female

0.430

  

NA

Age: ≤55 vs >55

0.967

  

NA

Serum AFP: ≤20 ng/ml vs >20 ng/ml

0.098

  

NA

Liver cirrhosis: no vs yes

0.568

  

NA

TNM: I vs II vs III

0.146

  

NA

Tumor encapsulation: no vs complete

0.046 a

  

NS

Tumor size: ≤5 cm vs >5 cm

<0.0001 a

0.376

0.213–0.662

0.001 a

Tumor number: single vs multiple

0.003 a

0.492

0.256–0.945

0.033 a

Tumor thrombus: single vs multiple

<0.0001 a

0.348

0.197–0.612

<0.0001 a

HOXD-AS1: low vs high

0.018 a

0.552

0.321–0.950

0.032 a

  1. Abbreviations: HCC hepatocellular carcinoma, HBsAg hepatitis B surface antigen, AFP α-fetoprotein, TNM tumor-nodes-metastases, HR hazard ratio, 95% CI 95% confidential interval, NA not applicable, NS not significant, astatistically significant