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Table 2 Multivariate analyses of factors associated with survival in 120 HCC patients

From: STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4

Variable Univariate p HR 95% CI p-value
Sex: male vs female 0.430    NA
Age: ≤55 vs >55 0.967    NA
Serum AFP: ≤20 ng/ml vs >20 ng/ml 0.098    NA
Liver cirrhosis: no vs yes 0.568    NA
TNM: I vs II vs III 0.146    NA
Tumor encapsulation: no vs complete 0.046 a    NS
Tumor size: ≤5 cm vs >5 cm <0.0001 a 0.376 0.213–0.662 0.001 a
Tumor number: single vs multiple 0.003 a 0.492 0.256–0.945 0.033 a
Tumor thrombus: single vs multiple <0.0001 a 0.348 0.197–0.612 <0.0001 a
HOXD-AS1: low vs high 0.018 a 0.552 0.321–0.950 0.032 a
  1. Abbreviations: HCC hepatocellular carcinoma, HBsAg hepatitis B surface antigen, AFP α-fetoprotein, TNM tumor-nodes-metastases, HR hazard ratio, 95% CI 95% confidential interval, NA not applicable, NS not significant, astatistically significant