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Fig. 1 | Molecular Cancer

Fig. 1

From: PRC1 contributes to tumorigenesis of lung adenocarcinoma in association with the Wnt/β-catenin signaling pathway

Fig. 1

PRC1 is upregulated in primary lung adenocarcinoma tissues. a Real-time RT-PCR analysis of PRC1 expression levels in lung adenocarcinoma (AD) tissues and paired adjacent non-tumoral tissues (n = 30). The mRNA levels of PRC1 in lung AD tissues are significantly higher than those in non-tumoral tissues. ***P < 0.005 (N, non-tumoral; T, tumor). b Expression levels of PRC1 protein in 12 paired primary lung AD tissues were determined by western blotting. Quantitative analysis of relative expression density is shown in the right panel. Each column represents the mean ± standard deviation (SD); ***P < 0.005 (N, non-tumoral; T, tumor). c Expression levels of PRC1 protein in TMAs (90 paired lung AD tissues and paired adjacent non-tumoral tissues) were determined by immunohistochemistry (IHC). Representative examples of PRC1 staining in lung cancer tissues and non-tumoral lung tissues are shown. Statistical analysis of PRC1 scores is shown in the right panel. ***P < 0.005

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