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Fig. 4 | Molecular Cancer

Fig. 4

From: Long non-coding RNA linc00673 regulated non-small cell lung cancer proliferation, migration, invasion and epithelial mesenchymal transition by sponging miR-150-5p

Fig. 4

Reciprocal correlation between linc00673 and miR-150-5p. a. The predicted binding sites of miR-150-5p to the linc00673 sequence. b. Association of miR-150-5p expression with overall survival of NSCLC patients, red: expression above upper quartile, blue: expression below upper quartile. c. Negative correlation between linc00673 and miR-150-5p expression in NSCLC patients. d. Association of linc00673 and miR-150-5p expression with pathologic stage in NSCLC patients. “Prophase” stands for stage I/II and “advanced” stands for stage III/IV. e. MiR-150-5p expression in 6 NSCLC cell lines and 1 human bronchial epithelial cell line as determined by qRT-PCR. f. Expression of linc00673 in miR-150-5p mimics transfected A549 cells as determined by qRT-PCR. g. Expression of linc00673 in miR-150-5p mimics transfected H1975 cells as determined by qRT-PCR. h. Expression of miR-150-5p in TGF-β treated A549 cells as determined by qRT-PCR. i. Expression of miR-150-5p in TGF-β treated H1975 cells as determined by qRT-PCR. Error bars indicate the mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.005

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Molecular Cancer

ISSN: 1476-4598